THE BIOLOGICAL EFFECTS
CALERIE was the first study of its kind to take an intensive behavioral approach to objectively measuring caloric restriction’s impacts on biologic effects through a randomized controlled trial.
CALERIE participants were healthy, nonobese humans of various gender and ethnic groups. Participants conformed to dietary modifications including, but not limited to, limited calorie intake, reduced portion size, specific meal plans, and low-carbohydrate diets. CALERIE participants incorporated particular behavioral strategies, group counseling sessions, and social support networks as a part of their participation in the calorie restriction group.