Just like the aging process is reflected on the surface of your skin, aging also occurs at the cellular level.
As humans age, the DNA damage we incur over the course of our lives results in nicotinamide adenine dinucleotide (NAD+) deficiency. As we get older, the presence of NAD+ molecules reduces, making our DNA less capable of repairing itself. Alongside NAD+, Coenzyme q10 (coq10) is found within every one of our cell’s mitochondria, and these enzymes are key players in cellular energy production. Without them, our mitochondria easily decays and leads to our outward and internal aging.
But at CALERIE®, we have observed these biological mechanisms that occur within our molecules and the role they play in aging. We mimic NAD+ production in order to slow the aging-process, restore cellular balance, and encourage longevity at our most foundational level.
Although we might not recognize the changes happening in our cells’ molecules, our lack of NAD+ makes itself physically apparent through the appearance of fine lines, wrinkles, and reduced collagen production. And NAD+ deficiency also becomes apparent through more life-threatening signs of the aging process. As our cells struggle to produce energy, humans can experience inflammation, increased blood pressure, oxidative stress, and other factors that lead to more severe health risks, like heart disease or heart attack.
Because our molecules are key players in all of our biological processes, vitamins and nutrients can only do so much in maintaining the balanced enzymes needed throughout the entirety of our lives.
Often called, the “fountain of youth,” the precursor enzymes nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) instigate NAD+ and Coq10 production, boosting the natural compounds that result in the best anti-aging prevention we’ve ever had as humans — our cells’ ability to naturally repair themselves.
For these reasons, NAD+ supplements like CALERIE® are able to operate as anti-aging supplements. Recent research has shown that consuming high doses of NAD+ in supplements like CALERIE® can slow the aging process and increase longevity. It also works in other ways beyond aging, and has shown to boost immune function, metabolism, and mimic the effects of calorie restriction to instigate weight loss.
NAD+ is not the only way to help prevent signs of aging.
Resveratrol, a natural compound with antioxidant properties found in the skin of berries and grapes, is known to have anti-aging effects. It’s one of the reasons drinking red wine has been known to have health benefits.
In addition, Vitamin D is crucial for guarding against UV damage and skin cancer. Your dermatologist will tell you that Vitamin E is a powerful antioxidant that helps repair skin damage. Combined with Vitamin C and Zinc, Vitamin E skin creams can help to heal visible scarring and instigate collagen repair.
But when a healthy, nutrient-packed diet includes both an RDA of vitamins and a NAD+ supplement, they combine to form a powerful, anti-aging dosage that restores the nicotinamide riboside and nicotinamide mononucleotide levels that are essential to our cellular function.
Not only do these anti-aging supplements have visible results in reduced wrinkles and inflammation, they can help fuel your immune system, improve brain function, and boost immunity.
There are a multitude of benefits that CALERIE® can instigate in the body, but unlike other dietary supplements, the power of NAD+ is being observed through animal research in Mayo Clinic labs and studied by nobel laureates and well-known biologists like Leonard P. Guarente.
Although NAD+ therapy has not been approved by the FDA, NR and NMN precursor supplements are sparking the curiosities of clinical researchers across the world. This is because of the impressive impact NAD+ mimetics have proven to have on taming free radicals and restoring our cellular functions.
The science of NR, NMN, and NAD+ is occupying clinical trials and research across the U.S. because of how successful NAD+ supplements have already proven to be in slowing the aging process in mammals.