Nicotinamide adenine dinucleotide (NAD+) is a molecule that appears during the human cellular energy production process. As older adults age, they experience NAD+ deficiency that leads to outward signs of the aging process like fine lines and wrinkles, chronic inflammation, and other age-related health concerns.

NMN is an alternative form of vitamin B3. They are NAD precursors, meaning they go through chemical processes to become the natural compound NAD+. NMN is converted into NAD+, a helper coenzyme that fuels many of the biological processes of mammals and is essential to energy production. NMN supplements instigate NAD production in mammals. They are essential in cellular health and mitochondrial function.

NAD+ deficiency can lead to major problems like cardiovascular conditions, insulin sensitivity, chronic inflammation, and loss of skeletal muscle. Decreased presence of the NAD precursor NMN also can lead to increased likelihood of obesity, cell death, decreased glucose metabolism, and overall degradation. NMN precursor supplements can help reduce the risk of many age-related conditions that occur in the aging process. Clinical trials have shown NAD boosters to help in prevention.

As we age, our bodies NAD production decreases because our cells lose the ability to repair themselves. Recent studies have suggested that increasing NAD levels after natural decline of NAD is one of the best anti-aging treatments. NAD boosters paired with multivitamins and proper nutrients can slow the aging process and may reduce the risk of metabolic conditions. Other dietary supplements do not consider how our cellular metabolism and mitochondria health are the foundation of our energy production processes. NAD are essential enzymes to our cellular systems, and NAD boosters can be a powerful preventative in combating the aging process.

CALERIE® instigates the activity of sirtuins to promote more cellular NAD production. For those desiring weight loss or obesity prevention, CALERIE® helps suppress appetite during periods of fasting. Previous studies have shown CALERIE® to reduce cravings and balance the cellular variables that impact energy consumption. Improved metabolic function, boosted NAD metabolism, and reduced oxidative stress are among the benefits of CALERIE® paired with a low-carbohydrate, high-nutrient, high-fat diet.

In the United states, nicotinamide mononucleotide supplements are becoming increasingly popular because of previous results in animal studies that have shown the effectiveness in raising NAD+ levels in rodents and old mice. NAD+ capsules can be used as both anti-aging supplements and as weight management and energy metabolism boosters, and the breadth of the benefits of sirt1 activity in mammalian cells has been observed across mouse studies.

Animal research has shown NAD+ to contribute to longevity. Clinical studies have shown that a daily dose of NAD+ supplements in mammals can stimulate the multiple biological processes that are fueled by the coenzyme. Further studies are being done to understand NAD role in increasing longevity.